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Figure 1 2 Pathogenesis of RA RA is an inflammatory disease caused by multi-cells communication and interaction by cytokines, which result in a variety of pathological reactions ( The cell-cell contact or cytokine signals from antigen-presenting cells (APCs) (especially Dendritic cells, DC) induced the conversion of T cells, B cells, synovial fibroblasts, osteoclasts and osteoblasts

The PRP (from the initial centrifugation) was collected and centrifuged for 5 minutes at 4 600 g , producing close to cell-free plasma and a platelet pellet

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The influence of the environment on the development of thyroid tumors: a new appraisal